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Ranked #2268 by analyst upside · 2026-06-27
SEPN
Septerna, Inc.
Healthcare · Market Cap $2B · P/E 0x
ANALYST PRICE TARGET
+22.6%
implied upside to consensus target
Current Price $37.34
Consensus Target $45.78
Bull Target $60.0
Bear Target $35.0
Analysts Covering 9
ANALYST CONSENSUS - BUY
Strong Buy
1
Buy
8
Hold
0
Sell
0
52-Week Low $10.26
52-Week High $37.99
YTD Return +33.5%
FUNDAMENTALS
Market Cap $2B
P/E Ratio (TTM) N/A
Forward P/E -14.0x
EPS (TTM) $-0.80
PEG Ratio N/A
Dividend Yield N/A
Revenue (TTM) $72M
Profit Margin -49.9%
52-WEEK RANGE
52-Week Low $10.26
52-Week High $37.99
Current Price $37.34
Bear Target $35.0
Bull Target $60.0
● Now $37.34 ● Target $45.78
TRADING DATA
Avg Volume 326K
YTD Return +33.5%
Analyst Count 9
Consensus Buy
Upside to Target +22.6%
Last Updated 2026-06-27

ANALYST SUMMARY

Septerna, Inc. (SEPN) is currently trading at $37.34 with a Wall Street consensus price target of $45.78, implying potential upside of 22.6% over the next 12 months. 9 analysts currently cover SEPN, with a consensus rating of Buy - 100% of analysts rate the stock a Buy or Strong Buy. The most bullish analyst has a price target of $60.0, while the most cautious has a target of $35.0.

SEPN operates in the Healthcare sector with a market capitalisation of $2B. The stock is up 33.5% year-to-date and is currently trading near the upper end of its 52-week range of $10.26 – $37.99.

SIMILAR STOCKS

Other Healthcare stocks with comparable size and valuation.

RECENT ANALYST CALLS

Upgrade/downgrade history for SEPN, with each firm's 90-day track record across all stocks we track. See full firm rankings →

Raymond James — Reiterated
Strong Buy → Strong Buy 2026-06-08 Building track record
HC Wainwright & Co. reit
Buy → Buy 2026-05-13 31% win rate (48 calls)
HC Wainwright & Co. reit
Buy → Buy 2026-04-14 31% win rate (48 calls)
JP Morgan — Reiterated
Overweight → Overweight 2026-03-24 43% win rate (7 calls)
Truist Securities — Reiterated
Buy → Buy 2026-03-11 Building track record
Wells Fargo — Reiterated
Overweight → Overweight 2026-03-03 Building track record
HC Wainwright & Co. — Reiterated
Buy → Buy 2026-03-02 31% win rate (48 calls)
HC Wainwright & Co. — Reiterated
Buy → Buy 2026-01-20 31% win rate (48 calls)
HISTORICAL SNAPSHOT

Point-in-time data from StockUpside's daily snapshots. Tracks price, analyst target, upside %, consensus, and analyst count.

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ANALYST CONVICTION SCORE
62
out of 100
Coverage depth
18/30
Consensus clarity
17/30
Vote unanimity
25/25
Rating stability
2/15

Measures analyst agreement, not fundamental quality. A high score means analysts broadly agree on this call - not that the stock will go up.

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