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Ranked #1937 by analyst upside · 2026-06-27
IONS
Ionis Pharmaceuticals, Inc.
Healthcare · Market Cap $13B · P/E 0x
ANALYST PRICE TARGET
+30.5%
implied upside to consensus target
Current Price $81.18
Consensus Target $105.91
Bull Target $130.0
Bear Target $75.0
Analysts Covering 23
ANALYST CONSENSUS — BUY
Strong Buy
6
Buy
10
Hold
6
Sell
1
52-Week Low $39.37
52-Week High $86.74
YTD Return +1.9%
FUNDAMENTALS
Market Cap $13B
P/E Ratio (TTM) N/A
Forward P/E -133.4x
EPS (TTM) $-2.01
PEG Ratio 27.33
Dividend Yield N/A
Revenue (TTM) $1.1B
Profit Margin -30.9%
52-WEEK RANGE
52-Week Low $39.37
52-Week High $86.74
Current Price $81.18
Bear Target $75.0
Bull Target $130.0
● Now $81.18 ● Target $105.91
TRADING DATA
Avg Volume 1.8M
YTD Return +1.9%
Analyst Count 23
Consensus Buy
Upside to Target +30.5%
Last Updated 2026-06-27

ANALYST SUMMARY

Ionis Pharmaceuticals, Inc. (IONS) is currently trading at $81.18 with a Wall Street consensus price target of $105.91, implying potential upside of 30.5% over the next 12 months. 23 analysts currently cover IONS, with a consensus rating of Buy — 70% of analysts rate the stock a Buy or Strong Buy. The most bullish analyst has a price target of $130.0, while the most cautious has a target of $75.0.

IONS operates in the Healthcare sector with a market capitalisation of $13B. The stock is up 1.9% year-to-date and is currently trading near the upper end of its 52-week range of $39.37 – $86.74.

SIMILAR STOCKS

Other Healthcare stocks with comparable size and valuation.

RECENT ANALYST CALLS

Upgrade/downgrade history for IONS, with each firm's 90-day track record across all stocks we track. See full firm rankings →

Leerink Partners — Reiterated
Outperform → Outperform 2026-06-17 29% win rate (7 calls)
TD Cowen reit
Buy → Buy 2026-06-15 Building track record
HC Wainwright & Co. reit
Buy → Buy 2026-06-01 31% win rate (48 calls)
Citigroup ● Initiated
Buy 2026-05-19 Building track record
RBC Capital — Reiterated
Outperform → Outperform 2026-04-30 Building track record
Barclays — Reiterated
Overweight → Overweight 2026-04-30 Building track record
HC Wainwright & Co. — Reiterated
Buy → Buy 2026-04-30 31% win rate (48 calls)
TD Cowen — Reiterated
Buy → Buy 2026-04-23 Building track record
HISTORICAL SNAPSHOT

Point-in-time data from StockUpside's daily snapshots. Tracks price, analyst target, upside %, consensus, and analyst count.

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ANALYST CONVICTION SCORE
out of 100
Coverage depth
0/30
Consensus clarity
0/30
Vote unanimity
0/25
Rating stability
0/15

Measures analyst agreement, not fundamental quality. A high score means analysts broadly agree on this call — not that the stock will go up.

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