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Ranked #1180 by analyst upside · 2026-08-13
IONS
Ionis Pharmaceuticals, Inc.
Healthcare · Market Cap $9B · P/E 0x
ANALYST PRICE TARGET
+58.0%
implied upside to consensus target
Current Price $56.53
Consensus Target $89.33
Bull Target $115.0
Bear Target $66.0
Analysts Covering 21
ANALYST CONSENSUS - BUY
Strong Buy
8
Buy
9
Hold
4
Sell
0
52-Week Low $41.54
52-Week High $86.74
YTD Return -29.0%
FUNDAMENTALS
Market Cap $9B
P/E Ratio (TTM) N/A
Forward P/E N/A
EPS (TTM) $-3.48
PEG Ratio 27.33
Dividend Yield N/A
Revenue (TTM) $874M
Profit Margin -64.7%
52-WEEK RANGE
52-Week Low $41.54
52-Week High $86.74
Current Price $56.53
Bear Target $66.0
Bull Target $115.0
● Now $56.53 ● Target $89.33
TRADING DATA
Avg Volume 2.9M
YTD Return -29.0%
Analyst Count 21
Consensus Buy
Upside to Target +58.0%
Last Updated 2026-08-13

ANALYST SUMMARY

Ionis Pharmaceuticals, Inc. (IONS) is currently trading at $56.53 with a Wall Street consensus price target of $89.33, implying potential upside of 58.0% over the next 12 months. 21 analysts currently cover IONS, with a consensus rating of Buy - 81% of analysts rate the stock a Buy or Strong Buy. The most bullish analyst has a price target of $115.0, while the most cautious has a target of $66.0.

IONS operates in the Healthcare sector with a market capitalisation of $9B. The stock is down 29.0% year-to-date and is currently trading near the lower end of its 52-week range of $41.54 – $86.74.

SIMILAR STOCKS

Other Healthcare stocks with comparable size and valuation.

RECENT ANALYST CALLS

Upgrade/downgrade history for IONS, with each firm's 90-day track record across all stocks we track. See full firm rankings →

Leerink Partners - Reiterated
Outperform → Outperform 2026-06-17 29% win rate (7 calls)
TD Cowen reit
Buy → Buy 2026-06-15 Building track record
HC Wainwright & Co. reit
Buy → Buy 2026-06-01 31% win rate (48 calls)
Citigroup ● Initiated
Buy 2026-05-19 Building track record
RBC Capital - Reiterated
Outperform → Outperform 2026-04-30 Building track record
Barclays - Reiterated
Overweight → Overweight 2026-04-30 Building track record
HC Wainwright & Co. - Reiterated
Buy → Buy 2026-04-30 31% win rate (48 calls)
TD Cowen - Reiterated
Buy → Buy 2026-04-23 Building track record
HISTORICAL SNAPSHOT

Point-in-time data from StockUpside's daily snapshots. Tracks price, analyst target, upside %, consensus, and analyst count.

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ANALYST CONVICTION SCORE
59
out of 100
Coverage depth
24/30
Consensus clarity
13/30
Vote unanimity
20/25
Rating stability
2/15

Measures analyst agreement, not fundamental quality. A high score means analysts broadly agree on this call - not that the stock will go up.

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